1969年8月出生于湖南,2003.8.-2005.7.:美国爱达荷大学,博士后研究
简介:(学习工作经历)中文和英文 1988.9.-1992.7.:湖南师范大学化学系,理学学士 1992.7.-1997.7.:湖南省邵阳师范高等专科学校,讲师 1997.8.-2000.8.:上海化工研究院,工学硕士 2000.8.-2003.7.:中国科学院上海有机化学研究所,理学博士 2003.8.-2005.7.:美国爱达荷大学,博士后研究 2005.8. 至今:中国科学院上海有机化学研究所,研究员,课题组长 1988.9.-1992.7.:Bachelor of Science, Department of chemistry, Hunan Normal University
1992.7.-1997.7.:Lecturer, Shaoyang Teachers College, Hunan Province 1997.8.-2000.8.:Master of Engineering, Shanghai Institute of Chemical Industry 2000.8.-2003.7.:Doctor of Philosophy, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences 2003.8.-2005.7.:Postdoctoral research, University of Idaho, USA 2005.8.- present:Professor, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
研究领域:中文和英文
1. 含氟功能分子的合成与反应:开发温和高效的氟化试剂,发展新颖氟化学反应,进行含氟药物分子和功能材料分子的合成 2. 绿色、高效分离纯化方法:针对组成复杂的混和物体系,发展高效分离试剂和绿色纯化方法 1. Synthesis and Reaction of Fluorine-containing Functional Molecules: Development of mild and efficient fluorination reagents; Development of novel organofluorine reactions; Synthesis of fluorine-containing pharmaceuticals, agrochemicals and functional materials
2. Green and Efficient Separation and Purification Method: Development of efficient separation reagents and green purification process for complex mixtures 代表性论文(工作业绩):
1. Yu, Jiao; Lin, Jin-Hong; Yu, Donghai; Du, Ruobing; Xiao, Ji-Chang* “Oxidation of difluorocarbene and subsequent trifluoromethoxylation” Nat. Commun. 2019, 10: 5362 doi: 10.1038/s41467-019-13359-z 2. Zhang, Min; Lin, Jin-Hong; Xiao, Ji-Chang* “Photocatalyzed Cyanodifluoromethylation of Alkenes” Angew. Chem. Int. Ed. 2019, 58, 6079-6083. 3. Zhang, Wei; Chen, Jia; Lin, Jin-Hong*; Xiao, Ji-Chang*; Gu, Yu-Cheng “Rapid Dehydroxytrifluoromethoxylation of Alcohols” iScience 2018, 5, 110-117. 4. Yu, Jiao; Lin, Jin-Hong*; Xiao, Ji-Chang* “Reaction of Thiocarbonyl Fluoride Generated from Difluorocarbene with Amines” Angew. Chem. Int. Ed. 2017, 56, 16669-16673. 5. Zheng, Jian; Cheng, Ran; Lin, Jin-Hong; Yu, Dong-Hai; Ma, Longle; Jia, Lina; Zhang, Lan; Wang, Lu; Xiao, Ji-Chang*; Liang, Steven H.* “An Unconventional Mechanistic Insight into SCF3 Formation from Difluorocarbene: Preparation of 18F-Labeled α-SCF3 Carbonyl Compounds” Angew. Chem. Int. Ed. 2017, 56, 3196-3200. 6. Deng, Zuyong; Lin, Jin-Hong; Xiao, Ji-Chang* “Nucleophilic arylation with tetraarylphosphonium salts” Nat. Commun. 2016, 7: 10337 doi: 10.1038/ncomms10337. 7. Zheng, Jian; Wang, Lu; Lin, Jin-Hong; Xiao, Ji-Chang*; Liang, Steven H.* “Difluorocarbene-Derived Trifluoromethylthiolation and [18F]Trifluoromethylthiolation of Aliphatic Electrophiles” Angew. Chem. Int. Ed. 2015, 54, 13236-13240. 8. Zhang, Cheng-Pan; Chen, Qing-Yun; Guo, Yong; Xiao, Ji-Chang*; Gu, Yu-Cheng. “Difluoromethylation and Trifluoromethylation Reagents Derived from Tetrafluoroethane β-Sultone: Synthesis, Reactivity and Applications” Coord. Chem. Rev. 2014, 261, 28-72. 9. Zhang, Cheng-Pan; Chen, Qing-Yun; Guo, Yong*; Xiao, Ji-Chang*; Gu, Yu-Cheng “Progress in fluoroalkylation of organic compounds via sulfinatodehalogenation initiation system” Chem. Soc. Rev. 2012, 41, 4536-4559. 10. Zhang, Cheng-Pan; Wang, Zong-Ling; Chen, Qing-Yun; Zhang, Chun-Tao; Gu, Yu-Cheng; Xiao, Ji-Chang*. “Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds by Trifluoromethyl Sulfonium Salts” Angew. Chem. Int. Ed. 2011, 50, 1896-1900.
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